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Author

E. Rossi

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Open access Sep 2026

Synergistic activity of colistin and stilbenoids against Pseudomonas aeruginosa clinical isolates

ABSTRACT Pseudomonas aeruginosa is a major opportunistic pathogen responsible for chronic lung infections in cystic fibrosis (CF) patients, contributing significantly to morbidity and mortality. In this study, we investigated the synergistic activity of colistin combined with two natural stilbenoids, pterostilbene and...

Nicola Mangieri, F. Annunziata, E. Rossi et al. · 0 citations
Open access Sep 2026

Resistance to antibacterial peptide nucleic acids through altered ribosome function

The ribosome–mRNA interface is identified as an intracellular determinant of antibacterial PNA susceptibility and rpsLI82N alters uS12-dependent 30S assembly and initiation-complex dynamics, thereby changing the effective occupancy of mRNA translation-initiation regions.

J. Frimodt-Møller, I. M. Roman, Thomas Prossliner et al. · 0 citations

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