Author

Elizabeth P. Henske

3 papers indexed here

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Open access Sep 2026

43 DSG2 and NPNT are Elevated in the Plasma of Metastatic Chromophobe RCC and are Associated with Poorer Overall Survival

Abstract Background Chromophobe renal cell carcinoma (ChRCC) is traditionally defined by its unique metabolic reprogramming, including an increase in mitochondrial mass. The mitochondrial plasma proteome of metastatic ChRCC has been recently reported (Steiner et al. Cancers 2026), and we defined a two-protein signature...

Tie-Gang Han, Clara Steiner, Steven Safi et al. · The Oncologist · 0 citations

Open access Sep 2026

42 Spatial Mapping of the Sarcomatoid Transition in Chromophobe Renal Cell Carcinoma Reveals a Reprogrammed Tumor-Immune Interactome

Abstract Background Chromophobe Renal Cell Carcinoma (ChRCC), derived from the intercalated cells of the collecting duct, typically follows an indolent clinical course. However, approximately 5–8% of cases undergo sarcomatoid transformation (sChRCC), a high-grade dedifferentiation resulting in a spindle-cell morphology...

Yan Tang, Tie-Gang Han, K. Collins et al. · The Oncologist · 0 citations

Open access Jul 2026

mTORC1 activation induces B7-H3-dependent metabolic reprogramming in renal cell carcinoma (RCC)

Renal cell carcinoma (RCC) affects over 435,000 people worldwide each year and remains a significant cause of cancer mortality. Aberrant activation of pathways such as mTORC1 is frequently observed in RCC, yet the mechanisms by which mTORC1 contributes to tumor development remain poorly understood. The lack of suitable...

Keying Li, H. Du, Yi-Fan Wang et al. · Oncogene · 0 citations