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Author

Elżbieta Płuciennik

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Open access Oct 2026

TFAP2E Expression Is Associated with Survival and a Transcriptomic Pattern in Ovarian Serous Carcinoma, Supported by Hallmark and Protein-Level Characterization

Background/Objectives: AP-2 transcription factors are increasingly recognized as key regulators in cancer biology. The TFAP2E gene, which encodes the AP-2ε transcription factor, remains understudied in cancer compared with other AP-2 family members. The scarcity of studies examining potential AP-2ε targets and related...

D. Kołat, Julia Gałęziewska, Paulina Buczek et al. · 0 citations
Review Open access Sep 2026

Parasites and allergies: a complex bidirectional relationship from evolutionary origins to modern therapeutics

Parasites and allergic diseases are linked by a complex, bidirectional relationship shaped by long-term host–parasite coevolution. This review discusses how different parasites may either promote or attenuate allergic responses through immunological, epithelial, and microbiome-mediated mechanisms. IgE-mediated immunity...

Kacper Packi, D. Świerczewski, Sylwia Klimczak et al. · 0 citations
Open access Aug 2026

ATM inhibition potentiates the anticancer activity of pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine sulfonamides in colorectal cancer cells in vitro

The results indicate that MM compounds exhibit measurable anticancer activity in 3D spheroid models and that their combination with ATM inhibition modulates both viability and spheroid morphology, as reflected by changes in ATP levels, core size, and diffusion parameters.

M. Kciuk, Katarzyna Wanke, M. Mojzych et al. · 0 citations

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