Author

Enrico Drago

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#gene editing Review Open access Aug 2026

SAVI: molecular mechanisms, clinical spectrum and precision medicine approaches beyond type-I IFN

The transition from immune - to a mutational-perspective, provides a foundational framework to optimize diagnostic and therapeutic strategies for precision medicine in SAVI patients.

Michele Manganelli, Paola Cantalice, Jona Papri et al. · Frontiers in Immunology · 0 citations

Open access Jul 2026

Non-genotoxic transplantation and in vivo selection through epitope editing

Epitope editing of KIT enables antibody-based, non-genotoxic conditioning that selectively enriches therapeutic BCL11A-edited haematopoietic stem/progenitor cells, supports durable engraftment, preserves clonal diversity and enhances induction of fetal haemoglobin, a therapeutic approach for conditions such as sickle c...

G. Casirati, Andrea Cosentino, Marta Freschi et al. · Nature · 0 citations