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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Ethan Yu

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#protein folding Open access Oct 2026

De Novo Design of High-Affinity Minibinders Targeting the Occluded Head-Interface Epitope of Influenza A Hemagglutinin

Influenza A viruses pose a persistent global health threat due to rapid antigenic drift in the hemagglutinin (HA) globular head. The monomer-monomer head-interface epitope is highly conserved across epidemic H3N2 strains but sterically occluded within the intact HA trimer, rendering it inaccessible to full-size monoclo...

Nolan Yu, Ethan Yu · 0 citations

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