Simple Summary Immunotherapy has improved outcomes for people with non-small-cell lung cancer, but some patients do not benefit or develop resistance during treatment. Blood tests known as liquid biopsies may help monitor cancer by detecting tumor-derived DNA and other circulating signals. This review examines their po...
T. D. Bazan Russo, V. Gristina, F. Pepe et al.· Cancers· 0 citations
The biological and clinical relevance of the epigenetic landscape of cfDNA in LC patients is explored, particularly focusing on DNA methylation-based biomarkers and their evolving applications towards early diagnosis and post-surgical monitoring of minimal residual disease (MRD).
T. D. Bazan Russo, V. Gristina, M. D. Delcuratolo et al.· Frontiers in Oncology· 0 citations
Beyond the attractive potential to surrogate the tumor tissue testing, to overcome the cancer spatial and temporal heterogeneity, and to monitor the tumor mutational profile over time, accurately detecting all clinically relevant BRCA genetic variants and epigenetic modifications using LB remains technically challengin...
L. Incorvaia, V. Gristina, F. Pepe et al.· ESMO Open· 0 citations
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