Matrix–Mechanical Genetic Susceptibility and Reduced Inflammatory and Immediate-Early Programs in Keratoconus
Purpose. To determine which proposed keratoconus (KC) mechanisms carry its genetic susceptibility and how it relates to corneal structure, and which describe its corneal tissue. Methods. Six mechanism modules and two attribution sets (transforming growth factor-β [TGF-β] and canonical type-2 atopy) were tested for enri...