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Fenglei Cao

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#protein folding Open access Sep 2026

Mechanical Programming of Hollow DNA Nanocapsules Rewires In Vivo Trafficking.

DNA nanostructures are programmable, biocompatible platforms for biomedicine; however, their mechanical properties are coupled to sequence and structural dimensions, limiting control over stiffness. Here, we report a paradigm shift from static design to mechanical engineering of DNA nanostructures. Using a nanoemulsion...

Fan Yang, Min-Chao Liu, Qian-Qian Lu et al. · 0 citations
Open access Aug 2026

Automated transition state generation for mechanistic exploration in organic synthesis

UniTS, a unified framework for automated transition state generation that combines a diverse transition state dataset with equivariant diffusion learning to accelerate mechanistic exploration, is developed.

Li-Cheng Xu, Jun-Yi An, Wei-Qi Liu et al. · 0 citations
Jul 2026

Monkey King Bang: A Unified Scientific Multimodal Foundation Model

Experiments show that MKB achieves competitive scientific understanding across biological and molecular benchmarks, produces high-fidelity native outputs for weather forecasting, biological generation, and medical-image segmentation, and largely retains the general capabilities of its Qwen3-VL backbone.

Hesen Chen, Xinyue Su, Xiaomeng Yang et al. · 0 citations

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