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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Francesco A. Aprile

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Open access Sep 2026

A Molecular Rotor-Based Platform for Dissecting Protein Phase Separation and Aggregation

Fluorescent probes based on molecular rotors, based on molecular rotors, with fluorescence lifetime imaging microscopy are combined to quantify changes in protein dynamics during phase separation-associated aggregate formation and provide quantitative, spatially resolved insights into structural transitions.

J. Gravell, Nicole Fitikides, Rebecca J. Thrush et al. · 0 citations
Review Open access Jul 2026

The sequence grammar and interactions controlling the aging of protein biomolecular condensates.

This review discusses how features of protein sequence, such as amino acid composition, interaction motifs, and post-translational modifications, influence condensate aging and highlights how interactions with RNA and lipid membranes modulate condensate behavior by altering interaction networks and interfacial properti...

Rebecca J. Thrush, Francesco A. Aprile · 0 citations

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