Author

Francesco Orilio

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Open access Oct 2026

Targeting CD44v6 and PI3K disrupts HGF-driven reprogramming of colorectal cancer stem cells

Therapeutic adaptive responses and secondary resistance represent major obstacles to effective colorectal cancer treatment. These dynamic adaptations arise within a permissive tumor microenvironment that sustains cancer cell survival, epithelial-mesenchymal plasticity and the outgrowth of drug-tolerant clones, ultima...

Kimiya Shams, Francesco Verona, Ornella Roberta Brancato et al. · Cell Death Discovery · 0 citations

Review 2026

miRNA Target Prediction: An Overview of the Past and Current Tools.

S. Di Bella, Francesco Orilio, G. Nigita et al. · Methods in molecular biology · 0 citations

Review 2026

isoTar: miRNA-Target Consensus Prediction with Enrichment Analysis for Canonical and Modified miRNAs.

S. Di Bella, Francesco Orilio, Shaopeng Gu et al. · Methods in molecular biology · 0 citations

2026

Computational Resources for Studying miRNA-lncRNA Interactions.

This chapter explores the biomedical significance of ceRNAs, highlighting their role in modulating gene expression and their potential implications in disease, and summarizes available tools, resources, and practical examples for studying lncRNA-miRNA interactions to aid researchers in navigating this sophisticated reg...

Francesco Orilio, R. Brancaccio, Francesco Verona et al. · Methods in molecular biology · 0 citations