#protein folding
Nov 2026
Transcriptomic effects of hydroxychloroquine in CD4+ T cells from patients with systemic lupus erythematosus: An exploratory pilot study.
Pre- and post-treatment transcriptomic evidence that HCQ exerts multifaceted immunomodulatory effects on CD4+ T cells, suppressing Th1-related, CD40, and histone pathways is provided, providing a molecular rationale for the clinical benefit of early HCQ introduction.
Fumito Abe, Masaya Saito, Ayano Saito et al.
· Lupus · 0 citations