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Author

G. Falcone

2 papers indexed here

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#protein folding Open access Oct 2026

Multiomics Profiling Supports Cathepsin B as a Protective Factor in White Matter Hyperintensities and Cognition

Background: White matter hyperintensities (WMH) are a common brain MRI marker of cerebral small vessel disease and a major risk factor for stroke and dementia, yet the molecular mechanisms governing lesion formation remain incompletely understood. We sought to identify circulating proteins that lie upstream of WMH and...

C. Rivier, Sebastián Díaz-Pérez, Gael Bories et al. · 0 citations
Open access Sep 2026

Multi-trait Polygenic Profiling and Survival Free of Dementia and Disability: Results from the Health and Retirement Study

ABSTRACT Objective: To determine whether a multi-trait polygenic profile for dementia is associated with dementia- and disability-free survival in middle-aged and older adults. Background: Clinical trials of brain health and aging increasingly use holistic, patient-centered outcomes that capture overall health status....

Y. Tawaldemedhen, S. Clocchiatti-Tuozzo, C. Rivier et al. · 0 citations

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