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Open access Oct 2026

Transcriptomic Profiling Reveals METTL26 as a Potential Biomarker in Head and Neck Squamous Cell Carcinoma with Independent Validation in Oral Squamous Cell Carcinoma

Background: Methyltransferase-like 26 (METTL26) is a poorly characterized member of the METTL family that has been included in previous pan-cancer analyses, but its disease-specific clinical and molecular relevance in head and neck squamous cell carcinoma (HNSCC) and oral squamous cell carcinoma (OSCC) remains poorly d...

Rossella Rotondo, A. Polizzi, S. Zeppa et al. · 0 citations
Review Sep 2026

Clinical Management of Oral Potentially Malignant Disorders: State of the Art Review and Proposal for a New Framework.

To address the absence of a unified weighting scheme for clinical and pathological predictors of malignant transformation in OPMDs, a targeted expert survey was conducted within the COST action INTERCEPTOR Working Group 2 (clinician-researchers with formal expertise in OPMDs).

H. Çobanoğlu, S. A. Khurram, A. Chaurasia et al. · 0 citations
Open access Oct 2026

Trueness and precision of 5 intraoral scanners under different conditions in arches: A 3D comparative in vitro analysis.

While the fully dentate model showed no significant differences in trueness among the scanners, it, along with the abutment model, yielded the highest overall accuracy, whereas the edentulous and scanbody models exhibited greater deviations.

A. Polizzi, Pietro Venezia, Sara Serra et al. · 0 citations
Review Open access Oct 2026

Biological Variability and Biomedical Innovation in Personalized Orthodontics: A Systematic Review with Narrative Synthesis

Personalized orthodontics should remain grounded in comprehensive diagnosis, biologically compatible mechanics, and individualized monitoring, but routine implementation requires standardized protocols, multicenter validation, and prospective evidence of patient-relevant benefit.

S. La Rosa, R. Leonardi, Vincenzo D'Antò et al. · 0 citations
Review Open access Oct 2026

Clinical and Genetic Characterization of a Family with Tooth Agenesis Carrying a Novel LEF1 Variant

Background: Tooth agenesis is one of the most common developmental anomalies of the human dentition and may occur either as an isolated trait or as part of a syndromic condition. Advances in genomic technologies have facilitated the identification of genes involved in odontogenesis, including LEF1 (Lymphoid Enhancer-Bi...

Ludovica Fortuna, Roberto Bertozzi, V. Trevisan et al. · 0 citations

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