Atherosclerotic cardiovascular diseases (ASCVD), including coronary artery disease (CAD), peripheral artery disease (PAD), and ischemic stroke (IS), account for the majority of global cardiovascular mortality. Although they affect distinct vascular territories, these conditions share overlapping traditional and g...
C. Abrahamian, L. Li, M. Ajayan et al.· European Heart Journal· 0 citations
AIMS
The etiology of coronary artery Disease (CAD) appears different for men and women, yet insights into underlying sex-specific biological mechanisms are limited. We integrated genomic and proteomic analyses to investigate sex-specific associations of the plasma-proteome with CAD.
METHODS AND RESULTS
In 40,829 UK B...
V. Sier, K. Dimitrova, E. Peters et al.· Cardiovascular Research· 0 citations
This study illustrates that GWAS with high-scale imputation may still help to unravel the biological mechanism behind circulating lipid levels and identifies more new rare and low-frequency functional variants associated with circulating lipid levels.
E. V. van Leeuwen, A. Sabo, J. Bis et al.· 0 citations
Plasma cfRNA was associated with calcification in carotid atherosclerotic plaques and may reflect aspects of underlying plaque biology and require validation in larger, independent populations.
Jian-Ming Wei, T. Lan, Yayuan Zhu et al.· npj Genomic Medicine· 0 citations
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