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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

George Wang

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Open access Sep 2026

Whole-exome sequencing in individuals with obsessive-compulsive disorder and chronic tic disorders identifies 36 large-effect risk genes.

Obsessive-compulsive disorder (OCD) and chronic tic disorders (CTDs) are highly heritable. Rare mutations confer large risks for OCD and CTDs but only four high-confidence (hc) genes have been identified. Here we analyzed whole-exome sequencing data from 3,964 individuals with OCD, CTDs or both, including 2,418 trios....

Belinda Wang, M. N. Tran, Sheng Wang et al. · 0 citations
Open access Aug 2026

Neuronal expression of bromodomain proteins alters neuronal health and peripheral protein homeostasis to promote longevity

It is shown that the neuronal expression of the chromatin reader BET-1 promotes longevity and resilience in C. elegans through signaling mechanisms involving master transcription factors HSF-1 and DAF-16 and neurotransmitter UNC-13.

Naibedya Dutta, Daniel Hicks, Edgar Esparza et al. · 0 citations

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