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Author

Giovanni Tonti

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Review Open access Sep 2026

Integration of multiple perspectives to understand the left ventricular pressure–volume relationship

For more than a century, the pressure–volume loop has offered a simple and elegant way to show how the heart pumps blood. In one picture, it summarizes how the heart fills, contracts, and ejects blood. However, this simplicity has a limitation: the loop treats the heart as if it were a single, uniform chamber. Therefor...

Giovanni Tonti, G. Pedrizzetti, Alessandro Salustri · 0 citations
Editorial Open access Oct 2026

Haemodynamic forces in aortic stenosis between myocardial function and valvular obstruction

The study by Backhaus et al. 1 enters a central debate in aortic stenosis: the search for the optimal timing of valve replacement has shifted attention from the valve to the myocardium.

Giovanni Tonti, Eduardo Bossone, G. Pedrizzetti · 0 citations

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