Gülfem Erbil

Timing the effort: Chronobiological drivers of skeletal muscle adaptation and metabolic health.

In conclusion, exercise timing represents an important regulator of metabolic health, and integrating circadian biology, nutritional timing, chronotype, sex, metabolic phenotype, and immune-metabolic context may facilitate the development of precision chrono-exercise strategies for metabolic and cardiometabolic disorde...

Why does siRNA delivery still fail in neurodegenerative diseases? Biological barriers, nanocarrier engineering, and future translational directions

The interplay between chronobiology, neuroinflammation, and the glymphatic system in neurodegenerative diseases

This conceptual review examines the highly interconnected, bidirectional crosstalk between the molecular circadian clock, glial-mediated neuroimmunity, and the macroscopic glymphatic clearance system and suggests that neurodegeneration can also be viewed as neurodegeneration as a network-wide collapse of biological tim...