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Guo-Fang Huang

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Sep 2026

Single-cell transcriptomics and multi-omics integration identify necroptosis-driven core targets and tubular-immune crosstalk in chronic kidney disease.

BACKGROUND Current pharmacotherapies for chronic kidney disease (CKD) are limited by adverse effects and a "one-target-one-drug" paradigm. Necroptosis is a key driver of renal deterioration, yet its regulatory network remains poorly defined. Modified Da-Huang-Fu-Zi Decoction (DHFZ) has shown clinical efficacy, although...

Si-Teng Zhang, Wei Zhu, Guo-Fang Huang et al. · 0 citations

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