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ADAR editing is established as an additional layer of immune regulation that may be contributing, in part, to the differential clinical manifestations of COVID-19 observed between males and females.
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by repetitive behavior and impaired social interactions. Recent reports from human postmortem brain samples of ASD show transcriptome-wide dysregulations, including changes in differential gene expression and alternative splicing. An importan...
Differences in expression and editing patterns of ADARs between critical and non-critical patients are demonstrated, supporting a potential role of ADAR editing in COVID-19 pathogenesis.
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