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H. Rye

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#protein folding Open access Sep 2026

Regulation of a Classical Allosteric Molecular Machine by an Intrinsically Disordered Domain: the C-termini of GroEL

A regulatory role is identified for the conserved, intrinsically disordered C-terminal tails of GroEL, one of the best-studied ATP-dependent chaperones, to reveal how the conformational properties of an intrinsically disordered element can be exploited to optimize the energetic efficiency and functional timing of a lar...

Morgan Powers, Kacie A. Evans, Sun He et al. · 0 citations

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