H. Siddiqui

Computational drug repurposing identifies flavoxate as a novel NLRP3 inflammasome inhibitor for Alzheimer’s disease therapy

By repurposing Flavoxate, this work proposes a clinically translatable strategy to mitigate NLRP3-mediated neuroinflammation in AD, offering a potential disease modifying therapy with an established safety profile and underscores the significance of computational approaches in bridging the gap between preclinical disco...