Venom-derived and natural analgesic peptides: From venomics-based discovery to computational design and therapeutic development.
Pain is a complex physiological process and an important clinical issue due to thelimitations of the existing analgesics. Side effects, tolerance anddependence, and limited efficacy for the treatment of chronic pain are common complications of classic drugs, e.g., opioids and nonsteroidal anti-inflammatory drugs (NSAID...