TL;DR
Findings suggest that Zeaxanthin and β-carotene, identified through a target-based chemoinformatics approach, could be considered as low-toxicity natural compounds with potential for topical or complementary applications in novel antifungal strategies.
Pegagan has strong potential as a source of environmentally friendly natural antifungal compounds and may be further developed as a biofungicide for controlling fungal diseases in oil palm plants.
Compound F4 emerges as a promising lead for antifungal drug development, distinguished by its broad‑spectrum activity, antibiofilm properties, and unique capacity to eliminate FLC tolerance.
Candida infections remain difficult to treat because of antifungal resistance, toxicity, and suboptimal pharmacokinetics. This study comparatively evaluated fourteen structurally diverse flavonoids against Candida albicans , Candida glabrata , and Candida krusei to identify structure–activity, mechanistic, a...
The findings indicate that the antifungal properties of Areca catechu are likely attributable to the combined action of multiple bioactive compounds, highlighting its potential as a natural source for developing environmentally friendly antifungal agents.
ABSTRACT To address the challenge of fungicide resistance in plant pathogenic fungi, coumarin derivatives were designed. Two series of coumarin derivatives, including 3‐amide and thienocoumarin ether derivatives, were designed and synthesized through structural modification of the coumarin scaffold to explore their ant...
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