Deciphering the role of APOBEC3B in t(4;14) multiple myeloma
Multiple myeloma (MM) is a genetically heterogeneous plasma cell malignancy characterized by recurrent chromosomal abnormalities and progressive genomic instability. Among these, the t(4;14)(p16;q32) defines a high-risk molecular subtype associated with poor clinical outcomes despite advances in therapy. This transloca...