Modeling spatiotemporal coupling is a key challenge in building physical intelligence across scales, from microscopic to macroscopic. Existing models capture such structure broadly through physics-motivated dynamical formulations or learning-motivated architectures. The former provide stronger priors but may constrain...
Yu-Hao Li, Louie Hong Yao, Tian-Yi Shi et al.· 0 citations
Diagnostics reveal that RL on PLMs is governed by two reward properties: verifiability, whether the reward is a fixed environment or a learned surrogate vulnerable to distribution shift, and coverage, the fraction of sequence space giving an informative gradient.
Hanqun Cao, Hongrui Zhang, Junde Xu et al.· Proceedings of the 32nd ACM...· 0 citations
Reinforcement learning (RL) is increasingly applied to Protein Language Models (PLMs), yet its effectiveness varies across tasks, and standard metrics such as pass@k can rise even when the model's solvable problem set is shrinking. We introduce two capability-level diagnostics. The Expansion-Shrinkage Ratio (ESR) measu...
Hanqun Cao, Hongrui Zhang, Junde Xu et al.· Proceedings of the 32nd ACM...· 0 citations
AgentFold is presented, a multi-agent framework that formulates folding-model development as a closed-loop search over executable code variants and improves the best lDDT by 7.5% over independent Codex proposals and outperforms a random-search control.
Ming-Quan Liu, Jiangyue Chen, Han-Qun Cao et al.· 0 citations
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