Glioblastoma (GBM) remains difficult to control. Monoclonal antibodies (mAbs) have transformed the treatment of several extracranial cancers, but they have not consistently improved survival in GBM. This narrative review examines the main biological and translational barriers to antibody-based therapy. It also evaluate...
Yang Zhou, You-Ming Li, Yu Chen et al.· Current Oncology· 0 citations
The hematoma clearance ratio was associated with long-term functional recovery after ICH surgery and provided performance comparable to the evaluated ML models and may serve as an interpretable research model.
Cheng Zhang, Yu-Chen Jiang, Jia-Qi Lin et al.· Frontiers in Neurology· 0 citations
Intracerebral hemorrhage (ICH) is associated with substantial morbidity and mortality, and early hematoma expansion (HE), defined as an increase in hematoma volume on follow-up imaging, is a major determinant of early neurological deterioration and poor outcomes. Accurate, hyperacute prediction of HE is critical for gu...
Hao-Liang Zhu, Tian-Yun Zhang, Hang-Zhe Sun et al.· Frontiers in Human Neuroscie...· 0 citations
The current applications of direct neuronal reprogramming technology in several neurological diseases are discussed and the potential contamination issues in adeno-associated virus (AAV) delivery systems are highlighted and a code of conduct is proposed to avoid artifacts and pitfalls.
Yu Chen, Zhe Zheng, Pei-Lei Zhao et al.· Frontiers in Neuroscience· 0 citations
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