Author

Hannah M. Doherty

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#protein folding Open access Oct 2026

Genome-wide synthetic lethality screen of Bam complex-associated genes in Escherichia coli

Abstract Biogenesis of the bacterial outer membrane is key to bacterial survival and antibiotic resistance. Central to this is the β-barrel assembly machine (Bam) complex and its associated chaperones, which are responsible for transport, folding and insertion of outer membrane proteins (OMPs). The Escherichia coli Bam...

Jack Alfred Bryant, Kara A Staunton, Hannah M. Doherty et al. · eLife · 1 citation

#protein folding Open access Sep 2026

Genome-wide synthetic-lethality screen of Bam complex associated genes in Escherichia coli

Biogenesis of the bacterial outer membrane is key to bacterial survival and antibiotic resistance. Central to this is the β-barrel assembly machine (Bam) complex and its associated chaperones, which are responsible for transport, folding and insertion of outer membrane proteins (OMPs). The Escherichia coli Bam complex...

Jack A. Bryant, Kara A Staunton, Hannah M. Doherty et al. · eLife · 0 citations