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Author

Hao Bo

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Aug 2026

Hongqi Shenmai Decoction ameliorates post-myocardial infarction heart failure by preserving mitochondrial cardiolipin homeostasis via attenuation of EGFR/JAK2-STAT3 signaling.

BACKGROUND Post-myocardial infarction heart failure (post-MI HF) is driven by adverse ventricular remodeling and mitochondrial dysfunction. Cardiolipin is essential for mitochondrial integrity, but its upstream regulation in failing myocardium remains unclear. Whether Hongqi Shenmai Decoction (HQSMD) preserves cardioli...

Hao Bo, Da Liu, Chunxia Zhai et al. · 0 citations
Aug 2026

Salvianolic acid a alleviates myocardial ischemia-reperfusion injury in rats via SIRT1-mediated inhibition of oxidative stress and inflammation.

SAA mitigates MIRI-induced oxidative stress and inflammation by activating SIRT1, which regulates the PGC-1α/Nrf2/HO-1 and NF-κB pathways, supporting SAA as a potential therapeutic agent for MIRI.

Zhen Chen, Yan-Ran Cao, Hao Bo et al. · 0 citations

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