LemonCatcher Acidic Pull-Down Enables Selective In-Cell Hydrogen-Deuterium Exchange Mass Spectrometry
LemonCatcher is created, a protein superglue that spontaneously forms an amide bond to the LemonTag peptide under these harsh acidic and cold quench conditions, even at -20 °C, and SelQueX makes possible selective characterization of protein structural dynamics within the complex cellular milieu.
Dietmar Hammerschmid, Mahjoobeh Eshani, A. H. Keeble et al.
· bioRxiv · 0 citations