Aug 2026
[CRISPR-Cas9 activation screening identifies candidate chemokine regulators of ter-tiary lymphoid structure formation in bladder cancer].
This study successfully identified CX3CL1 as a potential negative regulator of TLS formation in bladder cancer through CRISPR-Cas9 library screening combined with in vivo validation, and provides new clues and research directions for understanding the molecular mechanisms of TLS formation.
Yongcun Wang, Hong-Cheng Song, Yi-Qing Du et al.
· Beijing da xue xue bao. Yi x... · 0 citations