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Author

Hongwei Ye

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Aug 2026

Upregulation of YAP attenuates doxorubicin-induced cardiotoxicity through inhibiting ferroptosis.

BACKGROUND Doxorubicin (DOX) is a widely utilized anthracycline chemotherapeutic agent in clinical settings; however, its application is significantly constrained by the cardiotoxic effects it induces, the underlying mechanisms of which remain inadequately understood. Ferroptosis, a recently identified form of iron-dep...

Yuming Zhang, Anbo Zhao, Li Tang et al. · 0 citations
Aug 2026

[LCN2 knockout protects endothelial barrier function in mice with sepsis-induced acute lung injury by regulating the NF-κB signaling pathway].

LCN2 knockout alleviates sepsis-induced ALI and vascular endothelial dysfunction in mice by inhibiting NF-κB signaling and all changes were significantly ameliorated in LCN2KO mice and WT mice with NF‑κB inhibitor treatment.

Mengjie Yu, Anbo Zhao, Yixuan Hao et al. · 0 citations
Jul 2026

The potential mechanism investigation of Lipocalin-2 in ferroptosis via the AMPK/SIRT3/FOXO3a axis in sepsis-associated acute kidney injury.

Sepsis-associated acute kidney injury (SA-AKI) is a common and severe complication of sepsis. Lipocalin-2 (LCN2), a biomarker for SA-AKI, has an undefined role and underlying molecular mechanism in regulating renal ferroptosis. This study aimed to elucidate the regulatory function and potential mechanism of LCN2 in ren...

Linlin Zhang, Anbo Zhao, Hui Han et al. · 0 citations

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