Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy
ABSTRACT The clinical translation of engineered probiotics for inflammatory bowel disease (IBD) is hindered by limited intestinal retention and insufficient inflammation‐responsive precision. This study utilizes a surface display strategy to construct an adhesion‐enhanced Escherichia coli Nissle 1917 chassis. By presen...
Yu-Xi Wang, Pei-Chao Zhang, Si-Min Gu et al.
· Advancement of science · 0 citations