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Review Oct 2026

Insulin Resistance Markers Predict New-Onset Diabetes in Middle-Aged and Elderly Adults with Cardiovascular-Kidney-Metabolic Syndrome.

IR-related markers are significantly associated with the risk of diabetes in individuals with CKM syndrome and serve as reliable predictors of new-onset diabetes, highlighting their potential as valuable tools for early diabetes screening.

Yan-Ting Liang, Yu-Jian He, Jing-Yuan Liu et al. · 0 citations
Open access Aug 2026

Chronic kidney disease promotes anxiety susceptibility through an angiotensin II–central amygdala axis

These findings support a kidney-to-brain model in which CKD primes CeA stress circuits, while local Ang II–AT1R signaling contributes to the behavioral expression of stress-induced anxiety-like behavior, with a potential brain-to-kidney feedback component.

Yuting Liu, Yu-Jian He, Xinzhou Zhang et al. · 0 citations

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