Oct 2026· Current Medical Science· 0 citations· 30 references
Medicine
TL;DR
IR-related markers are significantly associated with the risk of diabetes in individuals with CKM syndrome and serve as reliable predictors of new-onset diabetes, highlighting their potential as valuable tools for early diabetes screening.
METS-IR and TyG-BMI demonstrated comparable and favorable performance, serving as practical, insulin-independent initial screening markers for identifying elevated IR risk in Chinese young and middle-aged adults without diabetes.
Jing-Yang Gao, Yunqiang He, Hemin Jiang et al.· Frontiers in Medicine· 0 citations
TyG-ABSI and TyG-WWI were the most consistent TyG-related body shape markers of all-cause mortality across international aging cohorts, suggesting that TyG-related body shape indices may serve primarily as interpretable, low-cost CKM risk markers rather than standalone prediction tools.
Fang-Ping Xiao, Hui Guo, Lei Wang et al.· Medicine· 0 citations
Higher TyG and SUA levels, particularly their co-occurrence, were associated with prevalent advanced CKM, suggesting these biomarkers may characterize distinct but overlapping metabolic profiles relevant to CKM assessment.
Sheng-Zhu Huang, Jing-Wei Lin, Ling-Yu Ye et al.· Frontiers in Nutrition· 0 citations
Metabolic and adiposity-related indices may help identify individuals at increased risk of cardiovascular-kidney-metabolic (CKM) progression; however, comparative prospective evidence remains limited. We examined the associations of seven metabolic and adiposity-related indices with progression to advanced CKM stag...
Type 2 diabetes mellitus (T2DM) has evolved into a global public health crisis characterized by high prevalence, chronic progression, and multisystem complications, including cardiovascular, renal, hepatic, and bone metabolic disorders. Insulin resistance (IR) serves as the core pathological driver of T2DM onset and...
Miao-Yan Yang, Jing Xu, Yun Sun et al.· Cardiovascular Diabetology· 0 citations
BACKGROUND
The triglyceride-glucose (TyG) index is a surrogate marker of insulin resistance with potential utility for assessing metabolic risk. However, the associations between the TyG index and related indicators and prediabetes/diabetes in U.S. adolescents remain unknown.
METHODS
This study included 5206 adolesce...
Jing-Li Wang, Cong-Cong Wei· Journal of the National Medi...· 0 citations
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