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Author

Hubert Łagosz

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#gene editing Review Open access Sep 2026

EDITING OUT CARDIOVASCULAR RISK: A NARRATIVE REVIEW OF GENE-EDITING APPROACHES TO PCSK9

Background: PCSK9 is a circulating protease that regulates plasma low-density lipoprotein (LDL) cholesterol levels. It binds to the LDL receptor on the surface of hepatocytes and directs the receptor toward intracellular degradation, so that greater PCSK9 activity leaves fewer LDL receptors available to clear LDL-C fro...

Piotr Bahyrycz, Karolina Markusiewicz, Magdalena Pyzik et al. · 0 citations
Review Open access Sep 2026

ARTIFICIAL INTELLIGENCE AND PRECISION MEDICINE IN OBESITY MANAGEMENT: CURRENT APPLICATIONS, CHALLENGES, AND FUTURE DIRECTIONS

Obesity is a complex, chronic, and heterogeneous disease that affects more than one billion people worldwide and represents one of the greatest public health challenges of the twenty-first century. Despite significant advances in pharmacotherapy, including glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and dual...

Alicja Włodarczyk, Hubert Łagosz, P. Wites et al. · 0 citations

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