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Author

Huei‐Ching Chiu

2 papers indexed here

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#gene editing Review Open access Sep 2026

Mitochondrial Quality Control in Inherited Mitochondrial Cardiomyopathy: Convergent Pathobiology and a Testable Therapeutic Framework

Inherited mitochondrial cardiomyopathies arise from pathogenic variants affecting oxidative phosphorylation, mitochondrial DNA maintenance, cardiolipin remodeling, protein import, cofactor metabolism, and mitochondrial dynamics or proteostasis. These disorders may be cardiac-predominant or part of multisystem disease....

Chung-Lin Lee, Chih-Kuang Chuang, Ya-Hui Chang et al. · 0 citations
#gene editing Open access Sep 2026

Mitochondrial Quality Control as the Mechanistic Hinge of Inherited Cardiomyopathy: Convergent Pathobiology and Targeted Therapy

Inherited mitochondrial cardiomyopathies arise from pathogenic variants that disrupt oxidative phosphorylation, mitochondrial DNA maintenance, cardiolipin biogenesis, or mitochondrial dynamics and quality control. Although the causative genes are diverse—mtDNA mutations, nuclear respiratory-chain and assembly factors,...

Chung-Lin Lee, Chih‐Kuang Chuang, Ya-Hui Chang et al. · 0 citations

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