We have 6 of 43 papers
We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.
Not the right person? Other researchers publish under this name.
Jiang et al. show that the type I-A CRISPR system of Saccharolobus islandicus recruits Cas3 only after target recognition. Their study reveals different Cas3 activation mechanisms and a dual role of ATP in target degradation and collateral cleavage.
Cancer immunotherapy faces significant challenges in treating “cold” tumors, which respond poorly to current strategies. Breast cancer is a major cause of cancer-related mortality in women and is a representative immunosuppressive cold tumor. The luminal A subtype of breast cancer exhibits an immune-cold phenotype, wit...
Evidence that agents capable of inducing ICD may instead promote cellular senescence when administered at lower concentrations for prolonged periods is highlighted, indicating that these distinct cellular outcomes can be determined by drug dose and treatment duration.
The structural, functional, and computational characterization of a chloramphenicol O-AT from Bacillus sp.
It is shown that Aca14, newly identified in this study, represses two predicted anti-defence operons and is a ribbon-helix-helix domain protein, revealing regulatory diversity beyond the canonical HTH Aca family members.
The crystal structure of AcrIIA17 is presented and its mechanism of Staphylococcus aureus Cas9 (SauCas9) inhibition is elucidated, identifying AcrIIA17 as an Acr protein that targets the Cas9 BH domain and reveal the BH domain as a regulatory checkpoint in Cas9 activation.
We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.
