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Author

I. Kovaleva

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Open access Sep 2026

The p53-Associated Regulation of ATF4 mRNA Expression Involves p21 and p130 in a Stress-Dependent Manner

Highlights What are the main findings? Chemotherapeutic agents targeting p53 downregulate ATF4 mRNA in a stress-dependent manner. p21 and p130 contribute to the specific p53-dependent downregulation of ATF4 mRNA upon mitochondrial dysfunction. ATF4 mRNA levels are reduced under hypoxic conditions and partially restored...

Alexandra A. Dalina, Maria Shilyaeva, I. Kovaleva et al. · 0 citations
#protein folding Open access Sep 2026

A Peculiar Phospholipid-Binding Specificity and Cell Death-Related Properties of Tubic (Nicotiana tabacum Tubby-like F-Box Protein 8)

Proteins possessing the Tubby domain (Tubby-like proteins, TLPs) are widespread in plants and represented by protein families. Although the function of TLPs is frequently associated with plant response to stresses, the mechanisms of their action are largely unknown. The recently demonstrated interaction of Tubic (Nicot...

Grigoriy G. Safronov, Artemii A. Pigidanov, R. A. Galiullina et al. · 0 citations

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