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Author

Iain P Hargreaves

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2 papers indexed here

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#gene editing Review Open access Nov 2026

COQ4 and COQ8A Primary Deficiencies: A Review of Proposed Therapeutic Strategies

In this article we have reviewed potential therapeutic strategies relating to two of the primary coenzyme Q10 (CoQ10) deficiencies, COQ4 and COQ8A; these disorders have been grouped together because of their complimentary roles in stabilising the CoQ10 enzyme complex, Complex Q, as well as the difficulty in treating ei...

D. Mantle, R. Heaton, Iain P. Hargreaves · 0 citations
Review Sep 2026

Mechanisms of Aging in Phenylketonuria (PKU).

A narrative review synthesizes the current evidence on accelerated aging in PKU, describes its clinical manifestations, and proposes potential aging biomarkers and treatment targets.

John Bassett, Neve Cufflin, Iain P Hargreaves et al. · 0 citations

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