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Isis N. O. Souza

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Open access Sep 2026

Principles of NMDA receptor co-agonism at cortical fast-spiking GABAergic interneurons in the adolescent prefrontal cortex

It is discovered that d-serine but not glycine is critical for maintaining the activity of NMDARs at FS-PV+ interneurons in the prelimbic area of the prefrontal cortex and that loss of its functions would recapitulate the synaptic deficits observed in several neuropsychiatric diseases like schizophrenia.

Isis N. O. Souza, Pierre Lecouflet, Zeynep Okur et al. · 0 citations

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