Identifying candidate genetic determinants associated with invasion in pneumococcal lineages
This work conducted a species-wide genome-wide association study of invasion and compared the prevalence of significant unitigs in GPSC1 and GPSC21 to identify invasion-associated variants differentiating them, and highlighted candidate proteins that may help explain invasiveness and could be explored as vaccine antige...
M. Pesonen, O. Lorenz, M. du Plessis et al.
· bioRxiv · 0 citations