Conformational ensembles of the disordered 4E‐BP2:eIF4E complex restrained by smFRET experiments
Full‐length atomistic conformational ensembles generated by IDPConformerGenerator and optimized by X‐EISDv2 workflow support a model of translation regulation in which the dynamic 4E‐BP2:eIF4E complex facilitates accessibility of regulatory sites of 4E‐BP2 when bound.
S. Smyth, Zi-Hao Liu, Thomas E. Tsangaris et al.
· Protein Science · 0 citations