These findings demonstrate that aberrant cortical folding in schizophrenia is constrained by network topology and molecular architecture, and establishes sulcal morphology as a mechanistically grounded biomarker that may help differentiate the neurodevelopmental trajectories of psychiatric disorders.
J. González-Peñas, H. Schnack, Carmen Rueda Hernández et al.· Biological Psychiatry· 0 citations
Findings suggest that part of SCZ liability reflects genetic susceptibility to SUDs with potential implications for patient stratification and clinical management.
S. Aranda, D. Koller, S. Papiol et al.· medRxiv· 0 citations
Prolonged CAL is linked to higher risk of FEP, preferentially affective psychosis in females, poorer functioning, and developmental potentiation of polygenic liability.
Á. Andreu-Bernabeu, J. González-Peñas, M. Bernardo et al.· Schizophrenia bulletin· 0 citations
This study finds that rare variants across hundreds of genes contribute to autism with variable phenotypic outcomes, and clusters them based on association evidence from large-scale studies of developmental disorders, schizophrenia, bipolar disorder, and epilepsy.
F. Satterstrom, C. Auwerx, J.-M. Fu et al.· medRxiv· 1 citation
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