Champollion, a self-supervised learning framework that learns interpretable local representations of cortical folding from structural MRI, is introduced, establishing cortical folding as a rich and largely untapped source of neurodevelopmental information.
Julien Laval, R. Guiavarch, Antoine Dufournet et al.· arXiv.org· 1 citation
Self-supervised representations of cortical folding are established as a powerful phenotype for the genetic study of neurodevelopment through multivariate genome-wide association studies (GWAS).
Antoine Dufournet, Julien Laval, J. Chavas et al.· bioRxiv· 0 citations
It is found that variation in primate social systems and/or reproductive aging may influence sex and species differences in brain aging, and within the baboons but not the chimpanzees, significant sex differences were found in age‐related differences in cortical folding.
William D Hopkins, Angela M. Achorn, M. M. Mulholland et al.· American Journal of Primatol...· 0 citations
This work believes this is the first evidence demonstrating an association between these clinically relevant biomarkers of Alzheimer’s disease and phenotypes of brain aging in nonhuman primates, underscoring their importance as models of aging and neurodegenerative disease.
M. Mulholland, Elizabeth R. Magden, Angela M. Achorn et al.· bioRxiv· 0 citations
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