Background Physical inactivity is a risk factor for severe COVID-19 and often worsens after hospitalisation. Clinicians need quick, accurate assessments to target interventions. We aimed to assess the validity of the General Practice Physical Activity Questionnaire (GPPAQ) in adults recovering 1 year after COVID-19 hos...
Lin Wang, K. Ntotsis, J. Manifield et al.· ERJ Open Research· 0 citations
BACKGROUND
Infants with non-specific symptoms are sometimes labelled as cow's milk allergic and managed with specialized formula. These products differ from standard infant formula in protein and carbohydrate source, typically containing lower quality protein and free/added sugars such as glucose polymers or sucrose. W...
N. Punjabi, Karen Li, Mark Cunningham et al.· Clinical and Experimental Al...· 0 citations
Low-dose computed tomography (LDCT) screening reduces lung cancer mortality through early detection. However, lung cancer screening uptake among high-risk groups remains low and varies by setting. This study aims to assess the factors associated with LDCT screening uptake among high-risk individuals.
We sear...
W. Mahikul, Yifei Huang, Jiawei Yuan et al.· ERJ Open Research· 0 citations
Biologic therapies offer new treatment opportunities for patients with eosinophilic COPD. However, the number and proportions of patients with COPD who would be eligible are unknown.
Using data from Optimum Patient Care Research Database, we conducted a retrospective observational study of electronic healt...
C. Schnier, P. McDowell, John Busby et al.· Respiratory Research· 0 citations
OBJECTIVES
Evidence used in NICE guidance has traditionally prioritised randomised controlled trials, but increasing availability of electronic health record (EHR) data has expanded opportunities for real-world evidence. The Clinical Practice Research Datalink (CPRD) is a commonly used UK primary care EHR resource, yet...
Alwin Paul, Ikenna Nwogu, Susan Hodgson et al.· Public Health· 0 citations
Abstract Objective To understand how prevalence estimates of single and multiple organ fibrosis have changed from 2012 to 2022. Design Retrospective population-based cohort study. Setting Data from primary (Clinical Practice Research Datalink Aurum) and secondary care (Hospital Episode Statistics Admitted Patient Care)...
G. M. Massen, Gisli R. Jenkins, R. Allen et al.· BMJ Open· 0 citations
Evidence of shared genetic associations for fibrosis across organs is found, both at individual genetic loci and genome-wide, which highlights specific genes that may contribute to fibrosis across organs and diseases, which may facilitate the development of new therapies.
Ebrima Joof, T. Hernández-Beeftink, G. Parcesepe et al.· BMJ Connections Clinical Gen...· 0 citations
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