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Oct 2026

THINKERS-X: multisequence MRI radiomics in a mixture-of-experts model for outcome prediction and exploratory dose-scenario evaluation in lung cancer brain metastases treated with radiosurgery

THINKERS-X improved lesion-specific longitudinal prediction, temporal accuracy, and probabilistic calibration beyond THINKERS-Lung while materially altering exploratory dose-scenario evaluation in a subset of metastases.

J. Reyes, Constantinos G. Hadjipanayis, A. Niranjan · 0 citations
Open access Sep 2026

Therapeutic hybrid intelligence with neural and knowledge-based expert reasoning for SRS: an AI model for breast cancer brain metastases

THINKERS-Breast provides an internally validated framework for tumor-specific local failure prediction and dose-policy evaluation after Gamma Knife radiosurgery for breast cancer brain metastases.

J. Reyes, A. Niranjan, Constantinos G. Hadjipanayis · 0 citations
Aug 2026

Stereotactic radiosurgery offers long-term tumor control for craniopharyngioma: a multi-institutional analysis of clinical and imaging outcomes from the International Radiosurgery Research Foundation (IRRF)

A retrospective multi-institutional cohort study including 296 patients from 13 centers, SRS achieved durable long-term control with favorable survival and low incidence of visual and endocrinologic dysfunction.

A. Niranjan, J. Reyes, Constantinos G. Hadjipanayis et al. · 1 citation

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