Skip to content

THINKERS-X: multisequence MRI radiomics in a mixture-of-experts model for outcome prediction and exploratory dose-scenario evaluation in lung cancer brain metastases treated with radiosurgery

Oct 2026 · Clinical and Experimental Metastasis · Vol 43 · 0 citations · 29 references
Medicine

TL;DR

THINKERS-X improved lesion-specific longitudinal prediction, temporal accuracy, and probabilistic calibration beyond THINKERS-Lung while materially altering exploratory dose-scenario evaluation in a subset of metastases.

View source

Similar papers

Open access Sep 2026

Therapeutic hybrid intelligence with neural and knowledge-based expert reasoning for SRS: an AI model for breast cancer brain metastases

THINKERS-Breast provides an internally validated framework for tumor-specific local failure prediction and dose-policy evaluation after Gamma Knife radiosurgery for breast cancer brain metastases.

J. Reyes, A. Niranjan, Constantinos G. Hadjipanayis · 0 citations
Oct 2026

Pretreatment MRI radiomics for predicting recurrence and metastasis after hypofractionated stereotactic radiosurgery in uveal melanoma.

MRI radiomics showed promising discrimination for local recurrence but limited discrimination for metastasis, and should be interpreted with caution given the small number of events in the test set and warrant external validation in larger cohorts.

Yusuf Baytar, Fırat Atak, G. Yazici et al. · 0 citations
Open access Oct 2026

Latest observed volumetric MRI response and lesion level local control after gamma knife radiosurgery for breast cancer brain metastases

Serial magnetic resonance imaging (MRI) reveals heterogeneous lesion responses after stereotactic radiosurgery beyond binary local-control status. We characterized latest-observed volumetric response categories after Gamma Knife radiosurgery (GKRS) for breast cancer brain metastases and examined their concordance...

Si-Jun Diao, Tao Huang, Zhong-Yu Li et al. · 0 citations
Oct 2026

Impact of multisequence MRI on deep learning-based dose prediction for glioblastoma radiotherapy: A comparative evaluation of CT-only and CT+MRI models.

INTRODUCTION Deep learning-based dose prediction has emerged as a promising approach for supporting automated radiotherapy planning workflows by estimating three-dimensional dose distributions from patient imaging. Although planning CT remains the standard imaging modality, multisequence MRI provides anatomical and tis...

S. Singh, S. Sen, A. Singh et al. · 0 citations
Open access Sep 2026

MRI Radiomics for Survival Prediction in Brain Metastases: A Machine Learning Analysis.

T1 postcontrast MRI radiomics showed limited standalone discrimination for overall survival in patients with brain metastases, which support cautious use of radiomics as an exploratory imaging biomarker and emphasize the need for integrated prognostic models that include clinical, treatment, molecular, and systemic dis...

H. Salim, Evan Calabrese, Ahmed Naeem et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.