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Author

Jean-François Mangin

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Open access Jul 2026

A Comparative Study of Aging and Cortical Folding in Chimpanzees and Olive Baboons

It is found that variation in primate social systems and/or reproductive aging may influence sex and species differences in brain aging, and within the baboons but not the chimpanzees, significant sex differences were found in age‐related differences in cortical folding.

William D Hopkins, Angela M. Achorn, M. M. Mulholland et al. · 0 citations
#protein folding Open access Aug 2026

Clinically Relevant Biomarkers of Alzheimer’s Disease Are Associated with Age and Cortical Atrophy in Chimpanzees (Pan troglodytes)

This work believes this is the first evidence demonstrating an association between these clinically relevant biomarkers of Alzheimer’s disease and phenotypes of brain aging in nonhuman primates, underscoring their importance as models of aging and neurodegenerative disease.

M. Mulholland, Elizabeth R. Magden, Angela M. Achorn et al. · 0 citations