Chaperone Networks at the Intersection of the Unfolded Protein Response and Oxidative Stress in Caenorhabditis elegans
Caenorhabditis elegans has served as a model for the unfolded protein response of the endoplasmic reticulum (UPR-ER) and, separately, the oxidative stress response coordinated by SKN-1/Nrf. The oxidative protein folding in the ER generates reactive oxygen species, which is one reason why these systems are frequently st...
Jerald Tan, Jirapan Thongsroy, Sirithip Chuaijit
· Stresses · 0 citations