Author

Ji Zheng

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Review Open access Aug 2026

Advances in understanding the tumor microenvironment of neuroendocrine prostate cancer

Neuroendocrine prostate cancer (NEPC) is an aggressive, treatment-refractory phenotype of advanced prostate cancer. This narrative review was informed by targeted searches of PubMed, Web of Science through May 2026. We classify evidence as Level A (human NEPC samples or clinical cohorts), Level B (NEPC-specific models)...

Nan Yao, Qi-Xing Yang, Peng-Kang Chang et al. · Frontiers in Oncology · 0 citations

Jul 2026

An Integrated Cell-Death Program Defines Aggressive Prostate Cancer by Coupling Ezrin to the Hippo–YAP/TAZ Axis

The AEN score is a robust prognostic tool linking PCD activity to PCa aggressiveness and immune evasion and EZR emerges as a functional effector and potential therapeutic target acting through Hippo signaling in PCa.

Xing Luo, Ze-Yu Huang, Min Deng et al. · Annals of Surgical Oncology · 0 citations

Aug 2026

Spatiotemporally Controlled Lysosomal Membrane Permeabilization Amplifies STING-Driven Antitumor Immunity in Prostate Cancer.

A spatiotemporally programmable supramolecular approach that integrates lysosomal disruption with innate immune activation to overcome therapeutic resistance and immunosuppression in PCa is established.

Qishu Jiao, Jiaqi Zhang, Chun-Lu Wang et al. · Advances in Materials · 0 citations